Advantages and Disadvantages of Shotgun Proteomics in Protein Identification
Shotgun proteomics has emerged as a powerful technique in the field of proteomics, enabling the comprehensive identification and quantification of proteins within complex biological samples. This high-throughput approach has revolutionized protein analysis, providing deep insights into the proteome. However, like any...
"De novo" sequencing is a technique in bioinformatics mainly used to determine the amino acid sequences of new or unknown proteins or peptides. Compared to re-sequencing, this technique pays special attention to those proteins or peptides that have not been identified or are not present in existing databases.
Why Do We Need De Novo Sequencing?
Although there are a large amount of known...
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