Plasmid DNA production is a vital aspect of molecular biology and biotechnology. Plasmids, which are small, circular pieces of DNA found in bacteria, serve as important tools for genetic engineering and cloning. The ability to produce plasmid DNA efficiently and in large quantities is essential for various applications, including gene therapy, vaccine development, and the production of...
In recent years, the agricultural sector has witnessed remarkable advancements, particularly in the realm of biotechnology. One of the key developments shaping the future of agriculture is the Plant Transformation Service. This innovative approach enables the modification of plant genomes to enhance desirable traits, thereby optimizing agricultural outputs and sustainability.
What is Plant...
Firefly luciferase, an enzyme derived from the bioluminescent firefly, has become an invaluable tool in molecular biology and biochemistry. Its ability to catalyze light-emitting reactions has not only captivated scientists’ imaginations but has also paved the way for groundbreaking research across various fields. The focus of this article is on the role of firefly luciferase mRNA in...
CRISPR/Cas9-derived RNA-guided nucleases (RGNs) are DNA targeting systems, which are rapidly being harnessed for gene regulation and gene editing purposes in cell lines and model organisms. As veritable gene delivery vehicles, viral vectors may be particularly fit to broaden the applicability of RGNs to other cell types including quiescent and dividing primary cells.
In this regard, adenoviral...
Viral vectors are a common tool for introducing new or corrected genes into human cells tor product cellular therapy products. Chimeric antigen receptor T (CAR T) cells require lentivirus to introduce the CAR gene into activated T cells. Lentiviral vectors have also been used for the treatment of hereditary disorders, such as severe combined immunodeficiency disorder (SCID) and Wiskott-Aldrich...
Oncolytic viruses (OVs) are an emerging treatment option for multiple cancer types and have recently been the focus of extensive research to develop their therapeutic potential. OVs have been put into the improvement of their efficacy and safety profiles. There are many viruses which either have naturally oncolytic properties or have been engineered to specifically lyse tumor cells. The great...
MicroRNAs (miRNAs) are a type of small single-stranded non-coding RNA molecules of 18 ~ 24 nucleotide (nt) in length. MiRNAs have been found in many species including plants, animals and some viruses. The conventional biosynthesis pathway consists of four steps: 1) miRNA genes are transcribed by RNA Polymerase II or III to produce pri-miRNAs, 2) pri-miRNAs are recognized and cleaved by...
Creative Biogene is the leading company offering the best recombineering based microbe genome editing services for a large wide range of microorganism species. With the assistance of our excellent scientists and technicians, we will complete your microbe genome editing project in a shot turnaround time with most competitive price.
Creative Biogene offers microorganism genome mutation,...
In the field of biological research, the ability to precisely edit the genetic material of organisms has revolutionized the way scientists study and understand biological processes. One of the most powerful tools for achieving this precision is the use of synthetic guide RNA (sgRNA), a key component of the CRISPR/Cas9 genome editing system. Custom synthesized sgRNA offers researchers a flexible...
IntegrateRNA uses the most powerful microarray platforms to provide you with the best miRNA expression profiling services that are constantly being validated, tested and updated. We have standard and custom microarrays for all mature miRNAs of all species available in miRBase V21.0 database. Our comprehensive service includes sample control, sample preparation and labeling, microRNA detection,...
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