Guidance Policy for Risk Assessment and RCL Testing
Viral vectors are a common tool for introducing new or corrected genes into human cells tor product cellular therapy products. Chimeric antigen receptor T (CAR T) cells require lentivirus to introduce the CAR gene into activated T cells. Lentiviral vectors have also been used for the treatment of hereditary disorders, such as severe combined immunodeficiency disorder (SCID) and Wiskott-Aldrich...
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