RNA-guided Nucleases (RGNs) Based CRISPR-Cas9
CRISPR/Cas9-derived RNA-guided nucleases (RGNs) are DNA targeting systems, which are rapidly being harnessed for gene regulation and gene editing purposes in cell lines and model organisms. As veritable gene delivery vehicles, viral vectors may be particularly fit to broaden the applicability of RGNs to other cell types including quiescent and dividing primary cells. In this regard, adenoviral...
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