KGN tumor cells are a specific cell line derived from human ovarian cancer, primarily utilized in research to gain insights into the biological mechanisms underlying tumor progression and potential therapeutic targets. This cell line has garnered attention due to its unique characteristics and relevance in the study of ovarian cancer.
Origin and Characteristics
The KGN cell line was...
Human skeletal muscle myoblasts play a crucial role in muscle development, repair, and regeneration. These specialized cells are fundamental to the formation of skeletal muscle tissue and are pivotal in maintaining muscle health throughout an individual’s life.
Myoblasts are mononucleated progenitor cells that originate from mesodermal stem cells during embryonic development. Once...
Cardiomyocytes, the muscle cells of the heart, play a crucial role in maintaining the organ’s function and overall health. Understanding these cells is essential for advancing treatments for various cardiovascular diseases. Traditionally, the study of cardiomyocytes came with significant limitations, primarily due to the difficulties associated with isolating and maintaining primary...
Genotoxicity refers to the harmful effects that certain substances can have on the genetic material within a cell. These effects can lead to mutations, cancer, and various other health problems. Therefore, assessing the genotoxic potential of compounds is critical in drug development, environmental safety, and regulatory compliance. Genotoxicity assay kits have emerged as essential tools for...
In the realm of pharmacology and drug development, understanding how a drug permeates biological membranes is crucial. In Vitro Permeability Assay Kits have emerged as vital tools for researchers to evaluate the permeability characteristics of various compounds across biological barriers. These kits are designed to mimic the physiological conditions present in the human body, thereby providing...
Primary human neurons are essential components in the study of the human nervous system, playing a pivotal role in advancing our understanding of neuronal development, function, and pathology. Unlike immortalized cell lines, primary human neurons are derived directly from human sources, showcasing authentic cellular characteristics that are vital for accurate research outcomes.
Isolating...
Reproductive toxicology is one of the most complicated areas of toxicology research due to the involvement of multiple organs and tissues, different modes of toxicant action and dependence on the endocrine system. In particular, endocrine disrupters represent a significant challenge for experimental toxicology because of their complex effects on signal networks and programming. A variety...
Animal studies are the gold standard for preclinical and translational studies of gastrointestinal (GI) disease. Although there are now specialized cell lines and "organs-on-a-chip" that provide in vitro platforms that can be used for drug selectivity and specificity studies, only whole-animal physiology can approximate clinical pathology and the effects of novel therapeutics....
High content screening (HCS), also known as automated microscope-based screening, measures the biological activity of a single cell or a whole organism after treatment with thousands of agents in a multi-well plate. Typically, the cell or organism are characterized by one or more fluorescent dyes, which leads to the term "high content".
Cell-based HCS has rapidly gained attention, as it is...
Creative Bioarray is an experienced and outstanding provider of cell-based Screening and profiling Services including cell-based high-throughput and high-content screening, specificity and selectivity profiling, and dose-response analysis. With our experienced scientific team and advanced technologies, we are able to quickly narrow down a large pool of candidates and identify effective...
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