The role of proteolytic enzymes in cellular function regulation has long been underestimated by the scientific realm. The identification of ubiquitin and its associated proteolytic enzymes has marked a revolutionary shift in scientific insights. Ubiquitin, a highly conserved molecule consisting of 76 amino acids, is ubiquitous in eukaryotic cells – hence its denomination. Its covalent...
What is Protein Glycosylation
Protein glycosylation denotes the enzymatic coupling of carbohydrate moieties, notably sugars, to predetermined amino acid residues within proteins, thereby yielding glycoproteins. This intricate biochemical phenomenon unfolds within the endoplasmic reticulum and Golgi apparatus, orchestrated by a heterogeneous ensemble of glycosyltransferases. Notably,...